2-4

Hypotension

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic effects of neuraxial block, hypovolaemia or combined causes. You should rapidly exclude a problem in adequate oxygen delivery, airway and breathing first.

START.
1
Adequate oxygen delivery
2
Airway
3
Breathing
4
Circulation
5
Depth
6
Surgical causes
7
Other causes & escalate
Box A CRITICAL CHANGES

If problem worsens significantly or a new problem arises, call for help and go back to START of 1-1 Key basic plan.

Box B ANTICHOLINERGIC DRUGS

Glycopyrrolate 5 µg.kg⁻¹ (adult 200–400 µg)

Atropine 5 µg.kg⁻¹ (adult 300–600 µg)

Box C VASOPRESSOR DRUGS

Ephedrine 100 µg.kg⁻¹ (adult 3–12 mg)

Phenylephrine 5 µg.kg⁻¹ (adult 100 µg)

Metaraminol 5 µg.kg⁻¹ (adult 500 µg)

Adrenaline 1 µg.kg⁻¹ (adult 10–100 µg) in emergency only

Box D SURGICAL CAUSES

Decreased venous return (e.g. vena cava compression / pneumoperitoneum)

Blood loss (unrecognised / undeclared / occult)

Vagal reaction to surgical stimulation

Embolism (gas / fat / blood / cement reaction)

Box E DON'T FORGET!

Consider whether you could have made a drug error.

Pneumothorax and/or high intrathoracic pressure can cause hypotension.

Also consider:

Cardiac ischaemia → 3-12

Anaphylaxis → 3-1

Cardiac tamponade → 3-9

Local anaesthetic toxicity → 3-10

Sepsis → 3-14

Cardiac valvular problem

Endocrine cause (e.g. steroid dependency)